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Recombinant Human Interleukin-17(rHu IL-17)

Product Specifications

CAS Number

9000-83-3

Synonyms

Cytotoxic T-lymphocyte-associated antigen 8, CLTA-8 , IL-17A

Source

Escherichia coli.

Purity

> 95 % by SDS-PAGE and HPLC analyses.

Bioactivity

Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5 ng/ml, corresponding to a specific activity of > 1.3 × 105 IU/mg.

Molecular Weight

Approximately 31.0 kDa, a disulfide-linked homodimer of two 132 amino acid polypeptide chains.

Storage Conditions

This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.

Formulation

Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.

Host or Source

Human

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