Recombinant Human Interleukin-17(rHu IL-17)
Product Specifications
Synonyms
Cytotoxic T-lymphocyte-associated antigen 8, CLTA-8 , IL-17A
Source
Escherichia coli.
Purity
> 95 % by SDS-PAGE and HPLC analyses.
Bioactivity
Fully biologically active when compared to standard. The ED50 as determined by inducing IL-6 secretion of murine NIH/3T3 cells is less than 7.5 ng/ml, corresponding to a specific activity of > 1.3 × 105 IU/mg.
Molecular Weight
Approximately 31.0 kDa, a disulfide-linked homodimer of two 132 amino acid polypeptide chains.
Storage Conditions
This lyophilized preparation is stable at 2-8 °C, but should be kept at -20 °C for long term storage, preferably desiccated. Upon reconstitution, the preparation is stable for up to one week at 2-8 °C. For maximal stability, apportion the reconstituted preparation into working aliquots and store at -20 °C to -70 °C. Avoid repeated freeze/thaw cycles.
Formulation
Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.
Host or Source
Human
CAS Number
9000-83-3
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