CD48 Recombinant Rabbit Monoclonal Antibody [JE37-98]
CD48 is a glycosylphosphatidylinositol (GPI) -anchored membrane protein of the signaling lymphocyte activation molecule (SLAM) family, also known as SLAMF2 and BLAST-1. It is constitutively expressed on most hematopoietic cells (not on neutrophils and a subset of long-term hematopoietic stem cells in mice) and can be upregulated under certain conditions like infection. Interaction with its low affinity ligand CD2 promotes adhesion and TCR signaling. Interaction with the high affinity ligand CD244 (2B4) regulates natural killer (NK) and CD8 T cell activation and cytolytic function.
Product Specifications
CAS Number
9000-83-3
Product Name Alternative
Abbreviation
CD48
Swiss Prot
P09326 Human, P18181 Mouse, P10252 Rat
Cellular Locus
Cell membrane, Secreted
Host
Rabbit
Species Reactivity
Human
Immunogen
Recombinant protein within Human CD48 aa 144-243 / 243.
Isotype
IgG
Clone
JE37-98
Conjugation
Non-conjugated
Type
Recombinant Rabbit monoclonal Antibody
Applications
WB, IHC-P
Positive Control
Raji cell lysate, Jurkat cell lysate, human colon tissue, human kidney tissue.
Concentration
1mg/mL
Dilution
WB: 1:1,000 ;IHC-P: 1:200-1:1,000
Purity
Protein A affinity purified.
Form
Liquid
Buffer
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Molecular Weight
Predicted band size: 27.7 kDa
Storage Conditions
Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze/thaw cycles.
Recombinant Antibody
Yes
Frequently Asked Questions
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