CCPA (hemihydrate)
CCPA (2-Chloro-N6-cyclopentyladenosine) hemihydrate a highly selective A1 adenosine receptors agonist with a Ki of 0.4 nM. CCPA hemihydrate selectively binds to adenosine A1 over adenosine A2 receptors (Ki of 3900 nM) . CCPA hemihydrate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1][2][3].
Product Specifications
CAS Number
1217443-91-8
Product Name Alternative
2-Chloro-N6-cyclopentyladenosine (hemihydrate)
UNSPSC
12352005
Target
Adenosine Receptor; Apoptosis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ccpa-hemihydrate.html
Solubility
10 mM in DMSO
Smiles
ClC(N=C1NC2CCCC2)=NC3=C1N=CN3[C@H]4[C@H](O)[C@H](O)[C@@H](CO)O4.O.[0.5]
Molecular Formula
C15H20ClN5O4.1/2H2O
Molecular Weight
378.81
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rat Matrix Metalloproteinase 12 (MMP12) ELISA Kit
Rat Matrix Metalloproteinase 12 (MMP12) ELISA Kit
Carboxypeptidase N subunit 2 (CPN2) (NM_001080513) Human Over-expression Lysate
Thyroglobulin (Thyroidal Cell Marker) (r6E1), CF647 conjugate, 0.1mg/mL
Alkaline Phosphatase Conjugated Rabbit Anti-WFA Antibody
