CCPA (hemihydrate)
CCPA (2-Chloro-N6-cyclopentyladenosine) hemihydrate a highly selective A1 adenosine receptors agonist with a Ki of 0.4 nM. CCPA hemihydrate selectively binds to adenosine A1 over adenosine A2 receptors (Ki of 3900 nM) . CCPA hemihydrate is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1][2][3].
Product Specifications
CAS Number
1217443-91-8
Product Name Alternative
2-Chloro-N6-cyclopentyladenosine (hemihydrate)
UNSPSC
12352005
Target
Adenosine Receptor; Apoptosis; Nucleoside Antimetabolite/Analog
Type
Reference compound
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer; Neurological Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/ccpa-hemihydrate.html
Solubility
10 mM in DMSO
Smiles
ClC(N=C1NC2CCCC2)=NC3=C1N=CN3[C@H]4[C@H](O)[C@H](O)[C@@H](CO)O4.O.[0.5]
Molecular Formula
C15H20ClN5O4.1/2H2O
Molecular Weight
378.81
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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