Tolfenpyrad (Standard)

Tolfenpyrad (Standard) is the analytical standard of Tolfenpyrad (HY-17516) . This product is intended for research and analytical applications. Tolfenpyrad is an orally active insecticide, acaricide and antibacterial agent. Tolfenpyrad inhibits Complex I in the mitochondrial respiratory electron transport chain, interfering with the cell respiration process. Tolfenpyrad has significant insecticidal activity against a variety of insect pests such as H. contortus, Coccinella septempunctata. Tolfenpyrad has antibacterial activity against Francisella novicida, with an IC50 of 1.2 µM or 1.5 µM[1][2][3][4][5][6][7][8].

Product Specifications

CAS Number

[129558-76-5]

UNSPSC

12352005

Target

Bacterial; Insecticide; Mitochondrial Metabolism; Reference Standards

Type

Reference Standards

Related Pathways

Anti-infection; Metabolic Enzyme/Protease; Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/tolfenpyrad-standard.html

Smiles

O=C(C1=C(Cl)C(CC)=NN1C)NCC2=CC=C(OC3=CC=C(C)C=C3)C=C2

Molecular Formula

C21H22ClN3O2

Molecular Weight

383.87

References & Citations

[1]Yamaguchi K, et al. Analysis of tolfenpyrad and its metabolites in plasma in a tolfenpyrad poisoning case. J Anal Toxicol. 2012 Sep;36 (7) :529-37.|[2]Hikiji W, et al. Acute fatal poisoning with Tolfenpyrad. J Forensic Leg Med. 2013 Nov;20 (8) :962-4.