Retinoic acid (Standard)
Retinoic acid (Standard) is the analytical standard of Retinoic acid. This product is intended for research and analytical applications. Retinoic acid is a metabolite of vitamin A that plays important roles in cell growth, differentiation, and organogenesis. Retinoic acid is a natural agonist of RAR nuclear receptors, with IC50s of 14 nM for RARα/β/γ. Retinoic acid bind to PPARβ/δ with Kd of 17 nM. Retinoic acid acts as an inhibitor of transcription factor Nrf2 through activation of retinoic acid receptor alpha.
Product Specifications
CAS Number
[302-79-4]
Product Name Alternative
Vitamin A acid (Standard) ; all-trans-Retinoic acid (Standard) ; ATRA (Standard)
UNSPSC
12352211
Hazard Statement
H302, H315, H360, H410
Target
Autophagy; Endogenous Metabolite; PPAR; RAR/RXR; Reference Standards
Type
Reference Standards
Related Pathways
Autophagy; Cell Cycle/DNA Damage; Metabolic Enzyme/Protease; Others; Vitamin D Related/Nuclear Receptor
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/retinoic-acid-standard.html
Purity
99.73
Smiles
CC1(C)C(/C=C/C(C)=C/C=C/C(C)=C/C(O)=O)=C(C)CCC1
Molecular Formula
C20H28O2
Molecular Weight
300.44
Precautions
H302, H315, H360, H410
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, sealed storage, away from light and moisture
Scientific Category
Reference Standards
Clinical Information
Launched
Isoform
Human Endogenous Metabolite; PPARα; PPARβ/δ; PPARγ
Available Sizes
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