Ac-Pro-Gly-Pro-OH
Ac-Pro-Gly-Pro-OH is an endogenous degradation product of extracellular collagen and can be used as CXCR2 agonist. Ac-Pro-Gly-Pro-OH elicits bactericidal activity and inhibits lung inflammation, reducing immune cell apoptosis. Ac-Pro-Gly-Pro-OH enhances the production of type 1 cytokines (IFN-γ and IL-12) but inhibits the production of proinflammatory cytokines. Ac-Pro-Gly-Pro-OH has the potential for the research of sepsis[1][2].
Product Specifications
CAS Number
292171-04-1
UNSPSC
12352209
Hazard Statement
H302
Target
CXCR
Type
Peptides
Related Pathways
GPCR/G Protein; Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ac-pro-gly-pro-oh.html
Purity
99.49
Solubility
H2O : 50 mg/mL
Smiles
O=C(N1[C@@H](CCC1)C(O)=O)CNC([C@H]2N(CCC2)C(C)=O)=O
Molecular Formula
C14H21N3O5
Molecular Weight
311.33
Precautions
H302
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
CXCR2
Available Sizes
Frequently Asked Questions
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