Procaspase-3/6 activator 1
Procaspase-3/6 activator 1 (compound 1541) is a highly specific and robust activator of executioner procaspases-3 and -6, with EC50 values of 2.4 ± 0.2 and 2.8 ± 0.3 μM, respectively. Procaspase-3/6 activator 1 does not activate procaspases-1 or -7[1].
Product Specifications
CAS Number
1100353-03-4
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Caspase
Type
Reference compound
Related Pathways
Apoptosis
Field of Research
Others
Assay Protocol
https://www.medchemexpress.com/procaspase-3-6-activator-1.html
Purity
99.45
Solubility
DMSO : 1 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C(C(NC2=CC=CC(C3=CN4C=CC=CC4=N3)=C2)=O)=CC5=CC=CC(OC)=C5O1
Molecular Formula
C24H17N3O4
Molecular Weight
411.41
Precautions
H302, H315, H319, H335
References & Citations
[1]Wolan DW, et al. Small-molecule activators of a proenzyme. Science. 2009 Nov 6;326 (5954) :853-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
Caspase 3; Caspase 6
Available Sizes
Frequently Asked Questions
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