What is the catalog number for TTNPB?

The catalog number for TTNPB is SIH-608-25MG.

What sizes are available for TTNPB?

TTNPB is available in the following size(s): 25 mg.

TTNPB is currently made to order / not held in immediate stock. Contact us for lead time.

TTNPB

Retinoic acid receptor agonist

Product Specifications

Background

TTNPB is an analog of retinoic acid that potently and selectively activates retinoic acid receptors (1). Enables chemical reprogramming (without genetic factors) of mouse embryonic fibroblasts to induced pluripotent stem (iPS) cells, in combination with CHIR99021, Tranylcypromine, Valproic Acid, 3-Deazaneplanocin A, and E-616452 (2). And it Induces the in vitro growth and differentiation to granulocytes of myeloid progenitors isolated from myelodysplastic syndrome (MDS) patients (3).

CAS Number

71441-28-6

Product Name Alternative

4-[ (E) -2- (5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl) -1-propenyl]benzoic acid; Ro 13-7410; AGN-191183

UNSPSC

41116105

Type

Agonist

Source

Synthetic

Field of Research

Cancer | Apoptosis | Stem Cells

Purity

>98% (HPLC) ; NMR (Conforms)

Weight

0.005

Format

Off-white powder

Solubility

May be dissolved in DMSO (4 mg/ml)

Molecular Formula

C24H28O2

Molecular Weight

348.5

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Beard R.L., et al. (1995) J Med Chem. 38 (15): 2820-2829. 2. Hou P. et al. (2013) Science. 341 (6146): 651-654. 3. Fabian I. (1987) Leukemia Research. 11 (7): 635-640.