SKA-31
KCa3.1 and KCa2 channel activator
Product Specifications
Background
SKA 31 is an activator of KCa3.1 and KCa2 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.
CAS Number
40172-65-4
Product Name Alternative
Naphtho[1,2-d]thiazol-2-ylamine
UNSPSC
41116105
Type
Activator
Source
Synthetic
Field of Research
Neuroscience | Neurotransmission | Neurotransmitter Receptors
Purity
>98% (TLC) ; NMR (Conforms)
Weight
0.005
Format
Off-white powder
Solubility
May be dissolved in DMSO (40mg/ml)
Molecular Formula
C11H8N2S
Molecular Weight
200.1
Precautions
Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.
References & Citations
1. Sankaranarayanan A., et al. (2009) Mol Pharmacol. 75 (2): 281-295.
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