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SKA-31

KCa3.1 and KCa2 channel activator

Product Specifications

Background

SKA 31 is an activator of KCa3.1 and KCa2 channels. It has significant blood-pressure reducing activity in experimentally hypertensive mice, suggesting potassium channel activation as a therapeutic target for hypertension.

CAS Number

40172-65-4

Product Name Alternative

Naphtho[1,2-d]thiazol-2-ylamine

UNSPSC

41116105

Type

Activator

Source

Synthetic

Field of Research

Neuroscience | Neurotransmission | Neurotransmitter Receptors

Purity

>98% (TLC) ; NMR (Conforms)

Weight

0.005

Format

Off-white powder

Solubility

May be dissolved in DMSO (40mg/ml)

Molecular Formula

C11H8N2S

Molecular Weight

200.1

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Sankaranarayanan A., et al. (2009) Mol Pharmacol. 75 (2): 281-295.

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