What is the catalog number for Baricitinib?

The catalog number for Baricitinib is SIH-587-5MG.

What sizes are available for Baricitinib?

Baricitinib is available in the following size(s): 5 mg.

Is Baricitinib in stock?

Baricitinib is currently made to order / not held in immediate stock. Contact us for lead time.

Baricitinib

Kinase inhibitor

Product Specifications

Background

Baricitinib acts as an inhibitor of janus kinase (JAK), blocking the subtypes JAK1 and JAK2, therby reducing cytokine release and suppressing the innate and adaptive immune systems. It was recently shown to significantly improve COVID-19 symptoms in a preliminary human trial, presumably through suppression of the cytokine release syndrome (“cytokine storm”) induced by SARS-CoV-2 infection.

CAS Number

1187594-09-7

Product Name Alternative

1- (Ethylsulfonyl) -3-[4- (7H-pyrrolo[2,3-d]pyrimidin-4-yl) -1H-pyrazol-1-yl]-3-azetidineacetonitrile, INCB028050, LY3009105

UNSPSC

41116105

Type

Inhibitor

Source

Synthetic

Field of Research

Cell Signaling | Growth Factors | TNF

Purity

>98% (HPLC) ; NMR (Conforms)

Weight

0.005

Format

White to off-white powder

Solubility

May be dissolved in DMSO (30 mg/ml); or DMF (50 mg/ml)

Molecular Formula

C16H17N7O2S

Molecular Weight

371.4

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1."Summary of opinion for Olumiant" (PDF). European Medicines Agency (EMA). 15 December 2016. 2. Cantini F., et al. (2020) J. Infect. DOI: 10.1016/j.jinf.2020.04.017