ATF4-IN-2
ATF4-IN-2 (Compound 29) is a ATF4 inhibitor with a IC50 value of 47.71 nM. ATF4-IN-2 can be used in the study of neurodegenerative diseases[1].
Product Specifications
CAS Number
2991057-60-2
UNSPSC
12352005
Target
Epigenetic Reader Domain
Type
Reference compound
Related Pathways
Epigenetics
Applications
Neuroscience-Neurodegeneration
Field of Research
Neurological Disease
Assay Protocol
https://www.medchemexpress.com/atf4-in-2.html
Purity
99.24
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(C1=NN=C(C2=CC=C(Br)C=C2)O1)NCC3CCN(NC(C4=CC5=CC(Cl)=CC=C5O4)=O)CC3
Molecular Formula
C24H21BrClN5O4
Molecular Weight
558.81
References & Citations
[1]Pei Y, et al. Design, Synthesis, and Biological Evaluation of Eukaryotic Initiation Factor 2B (eIF2B) Activators. ChemMedChem. 2024 Mar 1:e202300716.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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