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DENND4C Antibody: FITC

Mouse Anti-Human DENND4C Monoclonal IgG1

Product Specifications

Background

Dennd4c is a guanine nucleotide exchange factor (GEF) for Rab10, and required for GLUT4 translocation (1). It is associated with Alkuraya-Kucinskas Syndrome and Koolen-De Vries Syndrome (2) and interacts with the retromer (3).

Specifications

Detects ~213 kDa.

Product Name Alternative

DENN domain-containing protein 4C antibody

Synonyms

DENND4C Antibody: FITC

UNSPSC

12352203

Gene ID

55667

Swiss Prot

Q5VZ89

Accession Number

NM_017925

Cellular Locus

Cell membrane | Cytoplasm | Cytoplasmic vesicle | Membrane

Host

Mouse

Species Reactivity

Human,Mouse,Rat

Immunogen

Full Length Human Recombinant Dennd4c protein

Target

DENND4C

Clonality

Monoclonal

Isotype

IgG1

Clone

3E8

Conjugation

FITC

Tissue Specificity

Widely expressed

Validated Applications

IHC,ICC/IF

Purification

Protein G Purified

Limit Of Detection

A 1:1000 dilution of SMC-610 was sufficient for detection of DENND4C in A549, MEF cells by Western Blot analysis.

Concentration

1 mg/ml

Dilution

WB (1:1000); optimal dilutions for assays should be determined by the user.

Weight

0.1

Buffer

640.91mM DMSO, 136.36mM Ethanolamine, 9.09mM Sodium Bicarbonate in 90.9% PBS

Precautions

Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

References & Citations

1. Sano, H. et al. (2011). J Biol Chem. 286(19):16541-5. 2. https://www.genecards.org/cgi-bin/carddisp.pl?gene=DENND4C 3. McMillan, K. et al. (2016). J Cell Biol. 214(4):4389–418

Product Datasheet

https://cdn.gentaur.com/products/400/11821652/datasheet/smc-610d-fitc.pdf

Product MSDS

https://cdn.gentaur.com/products/400/11821652/msds/smc-610d-fitc.pdf

CAS Number

9007-83-4

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