L662,025
L662,025 is a specific, photolabile and irreversible Platelet-activating factor (PAF-receptor) antagonist, with IC50 values of 5.6 μM (platelet aggregation) and 1 μM (receptor binding), respectively[1].
Product Specifications
CAS Number
[122328-38-5]
UNSPSC
12352005
Target
Platelet-activating Factor Receptor (PAFR)
Type
Reference compound
Related Pathways
GPCR/G Protein
Field of Research
Metabolic Disease; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/l662-025.html
Smiles
COC1=C(OC)C(OC)=CC([C@H]2CC[C@H](C3=CC(OC)=C(OCC=C)C(N=[N+]=[N-])=C3)O2)=C1
Molecular Formula
C23H27N3O6
Molecular Weight
441.48
References & Citations
[1]I M Hussaini, et al. A SPECIFIC, PHOTOLABILE AND ANTAGONIST (L662,025) OF THE PAFRECEPTOR. Biochem Biophys Res Commun. 1989 May 30;161 (1) :23-30.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
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