2'-Deoxy-L-guanosine
2'-Deoxy-L-guanosine selectively inhibits D-Thymidine phosphorylation catalyzed by HSV 1 thymidine kinase. 2'-Deoxy-L-guanosine is the L-configuration of 2'-Deoxyguanosine (HY-17563) [1].
Product Specifications
CAS Number
[22837-44-1]
UNSPSC
12352005
Hazard Statement
H315, H319
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
COVID-19-anti-virus
Field of Research
Infection
Assay Protocol
https://www.medchemexpress.com/2-deoxy-l-guanosine.html
Purity
99.30
Solubility
DMSO : ≥ 100 mg/mL
Smiles
O[C@@H]1C[C@@H](N(C=N2)C(NC(N)=N3)=C2C3=O)O[C@H]1CO
Molecular Formula
C10H13N5O4
Molecular Weight
267.24
Precautions
H315, H319
References & Citations
[1]Spadari S, et al. L-thymidine is phosphorylated by herpes simplex virus type 1 thymidine kinase and inhibits viral growth. J Med Chem. 1992 Oct 30;35 (22) :4214-20.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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