NSC756093

NSC756093 is a potent inhibitor of the GBP1:PIM1 interaction. NSC756093 can potentially revert resistance to paclitaxel. NSC756093 can be used for ovarian cancer research[1].

Product Specifications

CAS Number

[1629908-92-4]

Product Name Alternative

SU093

UNSPSC

12352005

Hazard Statement

H302, H400

Target

Pim

Type

Reference compound

Related Pathways

JAK/STAT Signaling

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nsc756093.html

Purity

99.58

Solubility

DMSO : 62.5 mg/mL (ultrasonic)

Smiles

O=C1OCC(N2CCO)=C1C(C3=CC=CC=C3)C4=C2C=C(OC)C=C4

Molecular Formula

C20H19NO4

Molecular Weight

337.37

Precautions

H302, H400

References & Citations

[1]Andreoli M, et al. Identification of the first inhibitor of the GBP1:PIM1 interaction. Implications for the development of a new class of anticancer agents against paclitaxel resistant cancer cells. J Med Chem. 2014 Oct 9;57 (19) :7916-32.