L 888607
L 888607 is a potent, selective, stable and orally active CRTH2 agonist. L 888607 has high affinity for the human CRTH2 receptor with a Ki value of 4 nM. L 888607 can be used for the research of several physiological events and metabolite[1].
Product Specifications
CAS Number
860033-06-3
UNSPSC
12352005
Target
Prostaglandin Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology; Endocrinology
Assay Protocol
https://www.medchemexpress.com/L_888607.html
Purity
99.87
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C(O)C[C@@H]1CCN2C1=C(SC3=CC=C(Cl)C=C3)C4=C2C=C(F)C=C4
Molecular Formula
C19H15ClFNO2S
Molecular Weight
375.84
References & Citations
[1]Gervais FG, Identification of a potent and selective synthetic agonist at the CRTH2 receptor. Mol Pharmacol. 2005 Jun;67 (6) :1834-9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
DP; EP; FP; IP; TXA2/TP
Available Sizes
Frequently Asked Questions
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