Interleukin-9 (Human, Recombinant)

<strong>Interleukin-9 (Human, Recombinant)</strong>_x000D_ <strong>Catalog number:</strong> B2010313_x000D_ <strong>Lot number:</strong> Batch Dependent_x000D_ <strong>Expiration Date:</strong> Batch dependent_x000D_ <strong>Volume/Weight:</strong> 10 ug_x000D_ <strong>pH:</strong> 7.4 upon reconstitution_x000D_ <strong>Supplied as:</strong> Lyophilized Powder_x000D_ <strong>Appearance:</strong> Powder_x000D_ <strong>Applications:</strong> highly pure Interleukin-9 (Human, Recombinant) expressed in CHO. This protein acts as an immunoregulatory cytokine produced by IL-2-activated Th2 lymphocytes._x000D_ <strong>Storage:</strong> -20C_x000D_ <strong>Keywords:</strong> rHuIL-6; BSF-2; CDF; Hybridoma growth factor; IFN-beta-2_x000D_ <strong>Grade:</strong> Biotechnology grade. All components are highly pure (minimum 95%). All solutions are made with Type I ultrapure water (resistivity &gt;18 MΩ-cm) and are filtered through 0.22 um._x000D_ _x000D_ <strong>References:</strong>_x000D_ 1: Rauber S, Luber M, Weber S, Maul L, Soare A, Wohlfahrt T, Lin NY, Dietel K,_x000D_ Bozec A, Herrmann M, Kaplan MH, Weigmann B, Zaiss MM, Fearon U, Veale DJ, Cañete_x000D_ JD, Distler O, Rivellese F, Pitzalis C, Neurath MF, McKenzie ANJ, Wirtz S,_x000D_ Schett G, Distler JHW, Ramming A. Resolution of inflammation by_x000D_ interleukin-9-producing type 2 innate lymphoid cells. Nat Med. 2017_x000D_ Aug;23(8):938-944._x000D_ _x000D_ 2: Chakraborty S, Kubatzky KF, Mitra DK. An Update on Interleukin-9: From Its_x000D_ Cellular Source and Signal Transduction to Its Role in Immunopathogenesis. Int J_x000D_ Mol Sci. 2019 Apr 29;20(9):2113._x000D_ _x000D_ 3: Gerlach K, Weigmann B. The dichotomous function of interleukin-9 in cancer_x000D_ diseases. J Mol Med (Berl). 2019 Oct;97(10):1377-1383._x000D_ _x000D_ 4: Matusiewicz K, Iwańczak B, Matusiewicz M. Th9 lymphocytes and functions of_x000D_ interleukin 9 with the focus on IBD pathology. Adv Med Sci. 2018_x000D_ Sep;63(2):278-284._x000D_ _x000D_ 5: Zheng Y, He Y, Xiao M, Zhang W, Xia W, Hu H, Mao L, Liu A, Chen Z, Bai X, Li_x000D_ Y. Interleukin 9 prevents immune thrombocytopenia in mice via JAK/STAT5_x000D_ signaling. Exp Cell Res. 2020 Mar 1;388(1):111801._x000D_ _x000D_ 6: Doshi A, Khamishon R, Rawson R, Duong L, Dohil L, Myers SJ, Bell B, Dohil R,_x000D_ Newbury RO, Barrett KE, Kurten RC, Aceves SS. Interleukin 9 Alters Epithelial_x000D_ Barrier and E-cadherin in Eosinophilic Esophagitis. J Pediatr Gastroenterol_x000D_ Nutr. 2019 Feb;68(2):225-231._x000D_ _x000D_ 7: Ye D, Wang Z, Xu Y, Ye J, Wang M, Liu J, Zhang J, Zhao M, Chen J, Wan J._x000D_ Interleukin-9 aggravates doxorubicin-induced cardiotoxicity by promoting_x000D_ inflammation and apoptosis in mice. Life Sci. 2020 Aug 15;255:117844._x000D_ _x000D_ 8: Wharton W, Kollhoff AL, Gangishetti U, Verble DD, Upadhya S, Zetterberg H,_x000D_ Kumar V, Watts KD, Kippels AJ, Gearing M, Howell JC, Parker MW, Hu WT._x000D_ Interleukin 9 alterations linked to alzheimer disease in african americans. Ann_x000D_ Neurol. 2019 Sep;86(3):407-418._x000D_ <a href="https://pubmed.ncbi.nlm.nih.gov/32326670/">9: Park SM, Do-Thi VA, Lee JO, Lee H, Kim YS. Interleukin-9 Inhibits Lung_x000D_ Metastasis of Melanoma through Stimulating Anti-Tumor M1 Macrophages. Mol Cells._x000D_ 2020 May 31;43(5):479-490.</a>_x000D_ _x000D_ <strong>Products Related to Interleukin-9 (Human, Recombinant) </strong> <a href="https://moleculardepot.com/product-category/Proteins/">: Proteins</a>