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SK1-IN-1

SK1-IN-1 is a potent sphingosine kinase 1 (SPHK1) inhibitor with an IC50 of 58 nM.

Product Specifications

CAS Number

[1218816-71-7]

UNSPSC

12352005

Target

SphK

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-Kinase/protease

Field of Research

Cancer; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/SK1-IN-1.html

Purity

98.10

Solubility

DMSO : ≥ 100 mg/mL

Smiles

O=C([C@H]1NCC[C@@H]1O)N[C@H](C2=CC=C(C3=NOC(CCC4CCCC4)=N3)C=C2)C

Molecular Formula

C22H30N4O3

Molecular Weight

398.50

References & Citations

[1]Xiang Y, et al. Discovery of novel sphingosine kinase-1 inhibitors. Part 2. Bioorg Med Chem Lett. 2010 Aug 1;20 (15) :4550-4.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

SphK1

Available Sizes

Curated Selection

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