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1,7-Bis (4-hydroxyphenyl) -1,4,6-heptatrien-3-one

1,7-Bis (4-hydroxyphenyl) -1,4,6-heptatrien-3-one is a potent nucleocapsid (N) protein inhibitor can be isolated from Curcuma kwangsiensis. 1,7-Bis (4-hydroxyphenyl) -1,4,6-heptatrien-3-one exhibits excellent antiviral activity against HCoV-OC43 and SARS-CoV-2, with EC50 values of 0.16 μM and 0.17 μM, respectively[1].

Product Specifications

CAS Number

149732-52-5

UNSPSC

12352005

Target

SARS-CoV

Type

Natural Products

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/1-7-bis-4-hydroxyphenyl-1-4-6-heptatrien-3-one.html

Purity

95.51

Solubility

10 mM in DMSO

Smiles

OC(C=C1)=CC=C1/C=C/C=C/C(/C=C/C2=CC=C(C=C2)O)=O

Molecular Formula

C19H16O3

Molecular Weight

292.33

References & Citations

[1]Yang Liu, et al. 1,7-Bis (4-hydroxyphenyl) -1,4,6-heptatrien-3-one inhibits SARS-CoV-2 by targeting the nucleocapsid protein. Acta Materia Medica. 2023. Vol. 2 (3) :270-280.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Natural Products

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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