NRX-1532

NRX-1532 is a small molecule enhancer of β-catenin:β-TrCP interaction.

Product Specifications

UNSPSC

12352005

Target

β-catenin

Type

Reference compound

Related Pathways

Stem Cell/Wnt

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/nrx-1532.html

Purity

98.01

Solubility

DMSO : 250 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(NC1=O)C(F)(F)F)NC2=CC(C3=CC=NN3)=CC=C2

Molecular Formula

C16H11F3N4O2

Molecular Weight

348.28

References & Citations

[1]Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10 (1) :1402.

Shipping Conditions

Blue Ice

Storage Conditions

-20°C, 3 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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