NRX-1532
NRX-1532 is a small molecule enhancer of β-catenin:β-TrCP interaction.
Product Specifications
UNSPSC
12352005
Target
β-catenin
Type
Reference compound
Related Pathways
Stem Cell/Wnt
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/nrx-1532.html
Purity
98.01
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(NC1=O)C(F)(F)F)NC2=CC(C3=CC=NN3)=CC=C2
Molecular Formula
C16H11F3N4O2
Molecular Weight
348.28
References & Citations
[1]Simonetta KR, et al. Prospective discovery of small molecule enhancers of an E3 ligase-substrate interaction. Nat Commun. 2019 Mar 29;10 (1) :1402.
Shipping Conditions
Blue Ice
Storage Conditions
-20°C, 3 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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