Hexadimethrine bromide

Hexadimethrine bromide (Polybrene) is a cationic polymer used routinely to enhance the efficiency of retrovirus vector-mediated gene transfer[1][2].

Product Specifications

CAS Number

[28728-55-4]

Product Name Alternative

Polybrene; 1,5-Dimethyl-1,5-diazaundecamethylene polymethobromide

UNSPSC

12352211

Hazard Statement

H302

Target

Biochemical Assay Reagents

Type

Oligonucleotides

Related Pathways

Others

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Hexadimethrine_bromide.html

Purity

99.69

Solubility

DMSO : 5 mg/mL (ultrasonic; warming) |H2O : 100 mg/mL (ultrasonic)

Smiles

C[N+](CCCCCCC)(C)CCC[N+](C)(C)C.[Br-].[Br-].[n]

Molecular Formula

(C13H30N2Br2) n

Precautions

H302

References & Citations

[1]Lin P, et al. Polybrene inhibits human mesenchymal stem cell proliferation during lentiviral transduction. PLoS One. 2011;6 (8) :e23891.|[2]Abe A, et al. Polybrene increases the efficiency of gene transfer by lipofection. Gene Ther. 1998;5 (5) :708-711.