Stilbamidine (dihydrochloride)

Stilbamidine dihydrochloride is a diamidine compound derived from Stilbene and used chiefly in the form of its crystalline isethionate salt in treating various fungal infections.

Product Specifications

CAS Number

[6935-63-3]

Product Name Alternative

Ba 2652 (dihydrochloride) ; Stilbamidin (dihydrochloride)

UNSPSC

12352005

Target

Fungal

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/stilbamidine-dihydrochloride.html

Purity

95.44

Solubility

H2O : 1.96 mg/mL (ultrasonic; warming; adjust pH to 3 with HCl; heat to 60°C)

Smiles

N=C(N)C1=CC=C(C=C1)/C=C/C2=CC=C(C=C2)C(N)=N.Cl.Cl

Molecular Formula

C16H18Cl2N4

Molecular Weight

337.25

References & Citations

[1]De Koning HP. Uptake of pentamidine in Trypanosoma brucei brucei is mediated by three distinct transporters: implications for cross-resistance with arsenicals. Mol Pharmacol. 2001 Mar;59 (3) :586-92.|[2]BREWER AE.et al. Multiple myeloma treated with stilbamidine and pentamidine. Br Med J. 1948 Dec 4;2 (4587) :978-82.