STING agonist-17
STING agonist-17 (compound 4a) is a potent STING agonist with an IC50 value of 0.062 nM. STING agonist-17 has anti-cancer activity for tumor immunization[1].
Product Specifications
CAS Number
[2816929-47-0]
UNSPSC
12352005
Target
STING
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/sting-agonist-17.html
Purity
96.15
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
CCN1N=C(C=C1C(NC2=NC3=C(N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=CC(C(N)=O)=CC(OCCCNC(OC(C)(C)C)=O)=C64)C(OC)=CC(C(N)=O)=C3)=O)C
Molecular Formula
C43H53N13O8
Molecular Weight
879.96
References & Citations
[1]Min Jae Jeon, et al. Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor. J Med Chem. 2022 Apr 14;65 (7) :5407-5432.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS2907267-03 5x 96 Well
Human IGLV2-18/Immunoglobulin lambda variable 2-18 ELISA Kit
Ask
View Details MBS2907267-04 10x 96 Well
Human IGLV2-18/Immunoglobulin lambda variable 2-18 ELISA Kit
Ask
View Details N0019-03 50 µg
NAT1, Recombinant, Human, aa1-290, His-Tag (Arylamine N-acetyltransferase 1, AAC1, MNAT, NAT-1, NATI)
Ask
View Details 