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STING agonist-17

STING agonist-17 (compound 4a) is a potent STING agonist with an IC50 value of 0.062 nM. STING agonist-17 has anti-cancer activity for tumor immunization[1].

Product Specifications

CAS Number

[2816929-47-0]

UNSPSC

12352005

Target

STING

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/sting-agonist-17.html

Purity

96.15

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

CCN1N=C(C=C1C(NC2=NC3=C(N2C/C=C/CN4C(NC(C5=CC(C)=NN5CC)=O)=NC6=CC(C(N)=O)=CC(OCCCNC(OC(C)(C)C)=O)=C64)C(OC)=CC(C(N)=O)=C3)=O)C

Molecular Formula

C43H53N13O8

Molecular Weight

879.96

References & Citations

[1]Min Jae Jeon, et al. Development of Potent Immune Modulators Targeting Stimulator of Interferon Genes Receptor. J Med Chem. 2022 Apr 14;65 (7) :5407-5432.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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