PRMT6-IN-3
Product Specifications
UNSPSC Description
PRMT6-IN-3 (compound 25) is a selective PRMT6 inhibitor with an IC50 value of 192 nM. PRMT6-IN-3 can induce apoptosis in cancer cells and has anticancer activity[1].
Target Antigen
Apoptosis; Histone Methyltransferase
Type
Reference compound
Related Pathways
Apoptosis;Epigenetics
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/prmt6-in-3.html
Solubility
DMSO : 55 mg/mL (ultrasonic;warming)
Smiles
O=S(C1CC1)(NC2=CC=C(C3=CC(CN(C)CCNC)=CN=C3)C=C2)=O
Molecular Weight
374.50
References & Citations
[1]Qiangsheng Zhang, et al. Design, synthesis and evaluation of antitumor activity of selective PRMT6 inhibitors. Eur J Med Chem. 2022 Dec 20;247:115032.
Shipping Conditions
Room Temperature
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-152236/PRMT6-IN-3-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-152236/PRMT6-IN-3-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
2890765-10-1
Available Sizes
Curated Selection
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