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ZFY27 rabbit pAb

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010],

Product Specifications

Background

This gene encodes a protein with several transmembrane domains, a Rab11-binding domain and a lipid-binding FYVE finger domain. The encoded protein appears to promote neurite formation. A mutation in this gene has been reported to be associated with hereditary spastic paraplegia, however the pathogenicity of the mutation, which may simply represent a polymorphism, is unclear. [provided by RefSeq, Mar 2010]

UniProt

Q5T4F4

Swiss Prot

Q5T4F4

Reactivity

Human; Mouse; Rat

Immunogen

Synthesized peptide derived from human ZFY27 AA range: 351-401

Target

ZFY27

Clonality

Polyclonal

Source

Rabbit

Applications

WB

Concentration

1 mg/ml

Dilution

WB 1:500-2000

Buffer

-20°C/1 year

Storage Conditions

-20°C/1 year

Fragment

IgG

Subcellular Location

Recycling endosome membrane ; Multi-pass membrane protein . Endoplasmic reticulum membrane ; Multi-pass membrane protein . Cell projection, growth cone membrane ; Multi-pass membrane protein . Localizes at both dendrites and axons (By similarity) . Localizes to endoplasmic reticulum tubular network. .

Gene ID (Human)

118813

Available Sizes

Curated Selection

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