Pomalidomide-CO-C5-azide
Pomalidomide-CO-C5-azide (Compound PA) is a ligand for E3 ligase bearing a bioorthogonal group azide. Pomalidomide-CO-C5-azide can be used to synthesize PROTACs with anticancer activity[1].
Product Specifications
CAS Number
[2227423-33-6]
UNSPSC
12352005
Hazard Statement
H315-H319-H335-H372
Target
E3 Ligase Ligand-Linker Conjugates
Type
Reference compound
Related Pathways
PROTAC
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/pomalidomide-co-c5-azide.html
Solubility
10 mM in DMSO
Smiles
[N-]=[N+]=NCCCCCC(NC1=CC=CC(C(N2C3C(NC(CC3)=O)=O)=O)=C1C2=O)=O
Molecular Formula
C19H20N6O5
Molecular Weight
412.40
Precautions
P260-P264-P270-P271-P280-P302+P352-P304+P340-P305+P351+P338-P362-P403+P233-P405-P501
References & Citations
[1]Jie Zhang, et al. Self-assembly protein degradation agent with tumor cell specificity and preparation method and application thereof. Patent CN115260161A.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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