P-Nitrophenyl α-D-mannopyranoside

P-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149) ) [1][2].

Product Specifications

CAS Number

[10357-27-4]

Product Name Alternative

4-Nitrophenyl a-D-mannopyranoside

UNSPSC

12352200

Hazard Statement

H317, H319

Target

Glycosidase

Type

Biochemical Assay Reagents

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Assay Protocol

https://www.medchemexpress.com/p-nitrophenyl-α-d-mannopyranoside.html

Purity

99.68

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@@H]([C@H]([C@@H]1O)O)[C@H](O[C@@H]1CO)OC(C=C2)=CC=C2[N](=O)=O

Molecular Formula

C12H15NO8

Molecular Weight

301.25

Precautions

H317, H319

References & Citations

[1]Bols M, Hazell RG, Thomsen IB. 1‐Azafagomine: A hydroxyhexahydropyridazine that potently inhibits enzymatic glycoside cleavage. Chemistry–A European Journal. 1997 Jun;3 (6) :940-7.|[2]Bols M, Hazell RG, Thomsen IB. 1‐Azafagomine: A hydroxyhexahydropyridazine that potently inhibits enzymatic glycoside cleavage. Chemistry–A European Journal. 1997 Jun;3 (6) :940-7.