CGAS-IN-2
CGAS-IN-2 (compound 109) is a potent inhibitor of Cyclic GMP-AMP Synthase (cGAS), with IC50 of 0.01512 μM for h-cGAS[1].
Product Specifications
CAS Number
2765273-11-6
UNSPSC
12352005
Target
Cyclic GMP-AMP Synthase
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/cgas-in-2.html
Concentration
10mM
Purity
99.67
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
C[C@H]1C(C2=CC=C3Cl)=C(C[C@H](N1C(COC)=O)C)NC2=C3Cl
Molecular Formula
C16H18Cl2N2O2
Molecular Weight
341.23
References & Citations
[1]Ventus Therapeutics U.S., Inc. Pyrido[4,3-b]indole derivatives and their use as pharmaceuticals. World Intellectual Property Organization, WO2022066851 A1 2022-03-31
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
