Troxacitabine
Troxacitabine is nucleoside analog with potent anticancer activity.
Product Specifications
CAS Number
145918-75-8
Product Name Alternative
BCH 4556; L-OddC; SPD 758
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Nucleoside Antimetabolite/Analog
Type
Oligonucleotides
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Troxacitabine.html
Purity
99.95
Solubility
DMSO : 20 mg/mL (ultrasonic)
Smiles
NC1=NC(N(C=C1)[C@@H]2CO[C@H](CO)O2)=O
Molecular Formula
C8H11N3O4
Molecular Weight
213.19
Precautions
H302, H315, H319, H335
References & Citations
[1]Gourdeau H, et al. Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts. Cancer Chemother Pharmacol. 2002 Dec;50 (6) :490-6.|[2]Kadhim SA, et al. Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models. Cancer Res. 1997 Nov 1;57 (21) :4803-10.|[3]Weitman S, et al. The new dioxolane, (-) -2'-deoxy-3'-oxacytidine (BCH-4556, troxacitabine), has activity againstpancreatic human tumor xenografts. Clin Cancer Res. 2000 Apr;6 (4) :1574-8.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light)
Scientific Category
Oligonucleotides
Clinical Information
Phase 2
Available Sizes
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