Troxacitabine

Troxacitabine is nucleoside analog with potent anticancer activity.

Product Specifications

CAS Number

[145918-75-8]

Product Name Alternative

BCH 4556; L-OddC; SPD 758

UNSPSC

12352005

Hazard Statement

H302, H315, H319, H335

Target

Nucleoside Antimetabolite/Analog

Type

Oligonucleotides

Related Pathways

Cell Cycle/DNA Damage

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/Troxacitabine.html

Purity

99.95

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

NC1=NC(N(C=C1)[C@@H]2CO[C@H](CO)O2)=O

Molecular Formula

C8H11N3O4

Molecular Weight

213.19

Precautions

H302, H315, H319, H335

References & Citations

[1]Gourdeau H, et al. Antitumor activity of troxacitabine (Troxatyl) against anthracycline-resistant human xenografts. Cancer Chemother Pharmacol. 2002 Dec;50 (6) :490-6.|[2]Kadhim SA, et al. Potent antitumor activity of a novel nucleoside analogue, BCH-4556 (beta-L-dioxolane-cytidine), in human renal cell carcinoma xenograft tumor models. Cancer Res. 1997 Nov 1;57 (21) :4803-10.|[3]Weitman S, et al. The new dioxolane, (-) -2'-deoxy-3'-oxacytidine (BCH-4556, troxacitabine), has activity againstpancreatic human tumor xenografts. Clin Cancer Res. 2000 Apr;6 (4) :1574-8.