Bis (1-chloro-2-propyl) phosphate-d12

Bis (1-chloro-2-propyl) phosphate-d12 is deuterium labeled Bis (1-chloro-2-propyl) phosphate. Bis (1-chloro-2-propyl) phosphate (BCIPP) is a metabolite of organophosphate flame retardants (OPFR) that may alter energy metabolism by influencing the levels of steroid hormones, such as cortisol and cortisone. Bis (1-chloro-2-propyl) phosphate holds potential for research on metabolism-related diseases caused by environmental exposure[1][2].

Product Specifications

CAS Number

[1870073-89-4]

Product Name Alternative

BCIPP-d12

UNSPSC

12352211

Target

Endogenous Metabolite; Isotope-Labeled Compounds

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; Others

Field of Research

Metabolic Disease

Smiles

ClC([2H])(C(C([2H])([2H])[2H])(OP(OC(C([2H])([2H])[2H])(C([2H])(Cl)[2H])[2H])(O)=O)[2H])[2H]

Molecular Formula

C6HD12Cl2O4P

Molecular Weight

263.12

References & Citations

[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Ji Y, et al. Association between urinary organophosphate flame retardant diesters and steroid hormones: A metabolomic study on type 2 diabetes mellitus cases and controls. Sci Total Environ. 2021 Feb 20;756:143836.