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N-Acetylcysteine amide

Product Specifications

UNSPSC Description

N-Acetylcysteine amide is a cell membranes and blood brain barrier permeant thiol antioxidant and neuroprotective agent, reduces ROS production.

Target Antigen

Reactive Oxygen Species

Type

Reference compound

Related Pathways

Immunology/Inflammation;Metabolic Enzyme/Protease;NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology; Neurological Disease

Assay Protocol

https://www.medchemexpress.com/N-Acetylcysteine_amide.html

Purity

99.78

Solubility

DMSO : ≥ 100 mg/mL|H2O : 200 mg/mL (ultrasonic)

Smiles

CC(N[C@@H](CS)C(N)=O)=O

Molecular Weight

162.21

References & Citations

[1]Shi R, et al. N-acetylcysteine amide decreases oxidative stress but not cell death induced by doxorubicin in H9c2 cardiomyocytes. BMC Pharmacol. 2009 Apr 15;9:7.|[2]Pandya JD, et al. N-acetylcysteine amide confers neuroprotection, improves bioenergetics and behavioral outcome following TBI. Exp Neurol. 2014 Jul;257:106-13.|[3]Zhang X, et al. N-Acetylcysteine amide protects against methamphetamine-induced oxidative stress and neurotoxicity in immortalized human brain endothelial cells. Brain Res. 2009 Jun 12;1275:87-95.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-110256/N-Acetylcysteine-amide-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-110256/N-Acetylcysteine-amide-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

38520-57-9

Available Sizes

Curated Selection

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