CAY10444
CAY10444 (BML-241) is a sphingosine-1-phosphate 3 (S1P3) antagonist. CAY10444 inhibits by 37% S1P-induced increases in Ca2+ in HeLa cells expressing S1P3 receptors[1].
Product Specifications
CAS Number
[298186-80-8]
Product Name Alternative
BML-241
UNSPSC
12352005
Hazard Statement
H302, H315, H319
Target
LPL Receptor
Type
Reference compound
Related Pathways
GPCR/G Protein
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/cay10444.html
Concentration
10mM
Purity
98.0
Solubility
DMSO : 10 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C(O)[C@H]1NC(SC1)CCCCCCCCCCC
Molecular Formula
C15H29NO2S
Molecular Weight
287.46
Precautions
H302, H315, H319
References & Citations
[1]Salvatore Salomone, et al. Selectivity and specificity of sphingosine-1-phosphate receptor ligands: caveats and critical thinking in characterizing receptor-mediated effects. Front Pharmacol. 2011 Feb 22;2:9.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
S1PR3
Available Sizes
Curated Selection
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