CRGDfK-thioacetyl ester

CRGDfK-thioacetyl ester is a bioactive polypeptide molecule. cRGDfK peptide has a selective affinity for integrins. cRGDfK peptide can modify NIR fluorescent probes for cancer targeting imaging[1][2].

Product Specifications

CAS Number

[393781-65-2]

UNSPSC

12352209

Target

Integrin

Type

Peptides

Related Pathways

Cytoskeleton

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/crgdfk-thioacetyl-ester.html

Purity

98.57

Solubility

10 mM in DMSO

Smiles

O=C(N[C@H](C(N[C@H](C(NCC(N[C@H](C(N1)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)CCCCNC(CSC(C)=O)=O)[C@H]1CC2=CC=CC=C2

Molecular Formula

C31H45N9O9S

Molecular Weight

719.81

References & Citations

[1]Toti US, et al. Interfacial activity assisted surface functionalization: a novel approach to incorporate maleimide functional groups and cRGD peptide on polymeric nanoparticles for targeted drug delivery. Mol Pharm. 2010 Aug 2;7 (4) :1108-17. |[2]Gamage RS, et al. Comparison of cRGDfK Peptide Probes with Appended Shielded Heptamethine Cyanine Dye (s775z) for Near Infrared Fluorescence Imaging of Cancer. ACS Omega. 2021 Oct 30;6 (44) :30130-30139.