SARS-CoV S2 (sf9, His)

SARS-CoV spike glycoprotein 2 (S2) is a subunit of SARS-CoV Spike glycoprotein, among with S1 and S2'. S2 (668-1255) mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein, during endocytosis, S2 is cleaved into S2' (798-1255). Internalization into host cell endosomes induces S glycoprotein conformational changes, potentially unmasking the fusion peptide of S2 through cathepsin CTSL proteolysis. SARS-CoV S2 Protein (sf9, His) is the recombinant Virus-derived SARS-CoV S2 protein, expressed by Sf9 insect cells , with C-His labeled tag.