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Clavulanate (potassium)

Clavulanate potassium is a potent β-lactamase inhibitor and acts as an antibiotic[1][2].

Product Specifications

CAS Number

[61177-45-5]

UNSPSC

12352005

Hazard Statement

H228, H252, H317, H334

Target

Antibiotic; Bacterial; Beta-lactamase

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/clavulanate-potassium.html

Purity

99.45

Solubility

10 mM in H2O

Smiles

O=C([C@@H](/C(O[C@]1([H])C2)=C/CO)N1C2=O)O[K]

Molecular Formula

C8H8KNO5

Molecular Weight

237.25

Precautions

H228, H252, H317, H334

References & Citations

[1]Reading C, et al. Clavulanic Acid: a Beta-Lactamase-Inhibiting Beta-Lactam from Streptomyces clavuligerus. Antimicrob Agents Chemother. 1977 May; 11 (5) : 852–857.|[2]Stokes DH, et al. Bactericidal effects of amoxycillin/clavulanic acid against intracellular Legionella pneumophila in tissue culture studies. J Antimicrob Chemother. 1989 Apr;23 (4) :547-56.

Shipping Conditions

Room Temperature

Storage Conditions

4°C (Powder, sealed storage, away from moisture)

Scientific Category

Reference compound1

Clinical Information

Launched

Isoform

β-lactam

Citation 01

Biomed Res Int. 2018 Jul 2:2018:3579832.|bioRxiv. 2024 May 10.|Nat Commun. 2022 Mar 2;13 (1) :1116.|Eur J Pharmacol. 2024 Dec 5:984:177017.|Genomics. 2022 Nov;114 (6) :110527.|Int J Mol Sci. 2023 Oct 27;24 (21) :15657.|J Antimicrob Chemother. 2025 Nov 5:dkaf408.

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