Nifuroxazide-13C6
Nifuroxazide-13C6 is the 13C6 labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.
Product Specifications
UNSPSC
12352005
Target
Antibiotic; Bacterial; Isotope-Labeled Compounds; STAT
Type
Isotope-Labeled Compounds
Related Pathways
Anti-infection; JAK/STAT Signaling; Others; Stem Cell/Wnt
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection
Assay Protocol
https://www.medchemexpress.com/nifuroxazide-13c6.html
Solubility
10 mM in DMSO
Smiles
O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)[13C]2=[13CH][13CH]=[13C](O)[13CH]=[13CH]2
Molecular Formula
C6 13C6H9N3O5
Molecular Weight
281.17
References & Citations
[1]Nelson EA, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008 Dec 15;112 (13) :5095-102.|[2]Zhu Y, et al. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma. Sci Rep. 2016 Feb 2;6:20253.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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