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Nifuroxazide-13C6

Nifuroxazide-13C6 is the 13C6 labeled Nifuroxazide. Nifuroxazide is an effective inhibitor of STAT3, also exerts potent anti-tumor and anti-metastasis activity.

Product Specifications

UNSPSC

12352005

Target

Antibiotic; Bacterial; Isotope-Labeled Compounds; STAT

Type

Isotope-Labeled Compounds

Related Pathways

Anti-infection; JAK/STAT Signaling; Others; Stem Cell/Wnt

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Infection

Assay Protocol

https://www.medchemexpress.com/nifuroxazide-13c6.html

Solubility

10 mM in DMSO

Smiles

O=C(N/N=C/C1=CC=C([N+]([O-])=O)O1)[13C]2=[13CH][13CH]=[13C](O)[13CH]=[13CH]2

Molecular Formula

C6 13C6H9N3O5

Molecular Weight

281.17

References & Citations

[1]Nelson EA, et al. Nifuroxazide inhibits survival of multiple myeloma cells by directly inhibiting STAT3. Blood. 2008 Dec 15;112 (13) :5095-102.|[2]Zhu Y, et al. Nifuroxazide exerts potent anti-tumor and anti-metastasis activity in melanoma. Sci Rep. 2016 Feb 2;6:20253.|[3]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.

Shipping Conditions

Room temperature

Scientific Category

Isotope-Labeled Compounds

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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