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Oxyphenbutazone (monohydrate) (Standard)

Oxyphenbutazone monohydrate (Standard) is the analytical standard of Oxyphenbutazone monohydrate. This product is intended for research and analytical applications. Oxyphenbutazone monohydrate is a Phenylbutazone metabolite, with anti-inflammatory effect. Oxyphenbutazone monohydrate is an orally active non-selective COX inhibitor. Oxyphenbutazone monohydrate selectively kills non-replicating Mycobaterium tuberculosis[1][2].

Product Specifications

CAS Number

7081-38-1

UNSPSC

12352005

Target

Bacterial; COX; Reference Standards

Type

Reference compound

Related Pathways

Anti-infection; Immunology/Inflammation; Others

Field of Research

Infection; Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/oxyphenbutazone-monohydrate-standard.html

Smiles

O=C(C1CCCC)N(C2=CC=CC=C2)N(C3=CC=C(O)C=C3)C1=O.O

Molecular Formula

C19H22N2O4

Molecular Weight

342.39

References & Citations

[1]Saleem S, et al. Oxyphenbutazone promotes cytotoxicity in rats and Hep3B cellsvia suppression of PGE2 and deactivation of Wnt/β-catenin signaling pathway. Mol Cell Biochem. 2018 Jul;444 (1-2) :187-196.|[2]Gold B, et al. Nonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobials. Proc Natl Acad Sci U S A. 2012 Oct 2;109 (40) :16004-11.

Shipping Conditions

Room temperature

Scientific Category

Reference Standards

Frequently Asked Questions

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