ZINC00784494
ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC) [1].
Product Specifications
CAS Number
[317328-17-9]
UNSPSC
12352005
Target
Akt; Lipocalin Family
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease; PI3K/Akt/mTOR
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/zinc00784494.html
Purity
99.96
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C1C(C2=CSC(NC3=CC=CC(C(C)=O)=C3)=N2)=CC4=CC=CC=C4O1
Molecular Formula
C20H14N2O3S
Molecular Weight
362.40
References & Citations
[1]Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22 (16) :8581.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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