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ZINC00784494

Product Specifications

UNSPSC Description

ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC)[1].

Target Antigen

Akt

Type

Reference compound

Related Pathways

PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zinc00784494.html

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(C2=CSC(NC3=CC=CC(C(C)=O)=C3)=N2)=CC4=CC=CC=C4O1

Molecular Weight

362.40

References & Citations

[1]Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22(16):8581.

Shipping Conditions

Room Temperature

Product Datasheet

http://file.medchemexpress.com/batch_PDF/HY-148364/ZINC00784494-DataSheet-MedChemExpress.pdf

Product MSDS

http://file.medchemexpress.com/batch_PDF/HY-148364/ZINC00784494-SDS-MedChemExpress.pdf

Clinical Information

No Development Reported

CAS Number

317328-17-9

Available Sizes

Curated Selection

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