ZINC00784494

ZINC00784494 is a specific Lipocalin-2 (LCN2) inhibitor. ZINC00784494 inhibits cell proliferation, cell viability and reduces AKT phosphorylation levels in SUM149 cells. ZINC00784494 has good potential for research in inflammatory breast cancer (IBC) [1].

Product Specifications

CAS Number

[317328-17-9]

UNSPSC

12352005

Target

Akt; Lipocalin Family

Type

Reference compound

Related Pathways

Metabolic Enzyme/Protease; PI3K/Akt/mTOR

Applications

Cancer-Kinase/protease

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/zinc00784494.html

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C1C(C2=CSC(NC3=CC=CC(C(C)=O)=C3)=N2)=CC4=CC=CC=C4O1

Molecular Formula

C20H14N2O3S

Molecular Weight

362.40

References & Citations

[1]Santiago-Sánchez GS, et al. Targeting Lipocalin-2 in Inflammatory Breast Cancer Cells with Small Interference RNA and Small Molecule Inhibitors. Int J Mol Sci. 2021 Aug 10;22 (16) :8581.