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AJG049 (free base)

AJG049 free base is a calcium channel (Ca2+ channel) antagonist. AJG049 free base regulates vascular relaxation, reduces cardiac load, and improves cardiac perfusion by binding to the binding site of L-type calcium channels, specifically Diltiazem. AJG049 free base can be used in cardiovascular disease research[1].

Product Specifications

CAS Number

195991-49-2

UNSPSC

12352005

Target

Calcium Channel

Type

Reference compound

Related Pathways

Membrane Transporter/Ion Channel; Neuronal Signaling

Field of Research

Cardiovascular Disease

Assay Protocol

https://www.medchemexpress.com/ajg049-free-base.html

Smiles

COC(C=C1)=CC=C1CCN(CCC2)[C@H]2CN3C4=CC=CC=C4COC5=CC=CC=C53

Molecular Formula

C27H30N2O2

Molecular Weight

414.54

References & Citations

[1]Hashimoto M, et al. Comparative studies of AJG049, a novel Ca2+ channel antagonist, on voltage-dependent L-type Ca2+ currents in intestinal and vascular smooth muscle. Br J Pharmacol. 2006 Sep;149 (2) :155-62.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Frequently Asked Questions

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