Ontamalimab

Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1) . Ontamalimab can be used for the research of Crohn's disease[1].

Product Specifications

CAS Number

[2098790-40-8]

Product Name Alternative

SHP647

UNSPSC

12352203

Target

Integrin

Type

Inhibitory Antibodies

Related Pathways

Cytoskeleton

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/ontamalimab.html

Purity

99.86

Solubility

H2O

Smiles

[Ontamalimab]

Molecular Weight

(146.84 kDa)

References & Citations

[1]D'Haens GR, et, al. Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study. Inflamm Bowel Dis. 2022 Jul 1;28 (7) :1034-1044.