Ontamalimab
Ontamalimab (SHP647) is a fully-human IgG2 monoclonal antibody targeting mucosal addressin cell adhesion molecule-1 (MAdCAM-1) . Ontamalimab can be used for the research of Crohn's disease[1].
Product Specifications
CAS Number
[2098790-40-8]
Product Name Alternative
SHP647
UNSPSC
12352203
Target
Integrin
Type
Inhibitory Antibodies
Related Pathways
Cytoskeleton
Field of Research
Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/ontamalimab.html
Purity
99.86
Solubility
H2O
Smiles
[Ontamalimab]
Molecular Weight
(146.84 kDa)
References & Citations
[1]D'Haens GR, et, al. Long-Term Safety and Efficacy of the Anti-Mucosal Addressin Cell Adhesion Molecule-1 Monoclonal Antibody Ontamalimab (SHP647) for the Treatment of Crohn's Disease: The OPERA II Study. Inflamm Bowel Dis. 2022 Jul 1;28 (7) :1034-1044.
Shipping Conditions
Dry Ice
Storage Conditions
Store at -80°C for 2 years
Scientific Category
Inhibitory Antibodies
Clinical Information
Phase 3
Available Sizes
Curated Selection
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