UMB298

UMB298 is a potent and selective CBP/P300 bromodomain inhibitor[1].

Product Specifications

CAS Number

[2266569-73-5]

UNSPSC

12352005

Target

Epigenetic Reader Domain

Type

Reference compound

Related Pathways

Epigenetics

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/umb298.html

Concentration

10mM

Purity

99.28

Solubility

DMSO : 25 mg/mL (ultrasonic)

Smiles

CC1=C(C2=CC3=NC(CCC4=CC=C(OC)C(Cl)=C4)=C(NC5CCCCC5)N3C=C2)C(C)=NO1

Molecular Formula

C27H31ClN4O2

Molecular Weight

479.01

References & Citations

[1]Muthengi A, et al. Development of Dimethylisoxazole-Attached Imidazo[1,2-a]pyridines as Potent and Selective CBP/P300 Inhibitors. J Med Chem. 2021;64 (9) :5787-5801.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

BRD4

Available Sizes

Curated Selection

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