Nampt-IN-1
Product Specifications
Product Name Alternative
LSN3154567
UNSPSC Description
Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
Target Antigen
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Nampt-IN-1.html
Purity
99.48
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(C=C(NS(CC(C)(C)O)(=O)=O)C=C2)=C2C1)COC3=CN=CC=C3
Molecular Weight
419.49
References & Citations
[1]Zhao G, et al. Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration. Mol Cancer Ther. 2017 Dec;16(12):2677-2688.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Product Datasheet
http://file.medchemexpress.com/batch_PDF/HY-12971/Nampt-IN-1-DataSheet-MedChemExpress.pdf
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-12971/Nampt-IN-1-SDS-MedChemExpress.pdf
Clinical Information
No Development Reported
CAS Number
1698878-14-6
Available Sizes
Curated Selection
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