Nampt-IN-1
Nampt-IN-1 (LSN3154567) is a potent and selective NAMPT inhibitor. Nampt-IN-1 inhibits purified NAMPT with an IC50 of 3.1 nM.
Product Specifications
CAS Number
[1698878-14-6]
Product Name Alternative
LSN3154567
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
NAMPT
Type
Reference compound
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/Nampt-IN-1.html
Purity
99.48
Solubility
DMSO : 175 mg/mL (ultrasonic)
Smiles
O=C(N1CCC(C=C(NS(CC(C)(C)O)(=O)=O)C=C2)=C2C1)COC3=CN=CC=C3
Molecular Formula
C20H25N3O5S
Molecular Weight
419.49
Precautions
H302, H315, H319, H335
References & Citations
[1]Zhao G, et al. Discovery of a Highly Selective NAMPT Inhibitor That Demonstrates Robust Efficacy and Improved Retinal Toxicity with Nicotinic Acid Coadministration. Mol Cancer Ther. 2017 Dec;16 (12) :2677-2688.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
More Discoveries
Explore Other Products
Browse additional items from our catalog
484730 100 µL
LGALS14 (Placental Protein 13-Like, Lectin, Galactoside-Binding, Soluble, 14)
Sign In for Pricing
View Details 
MK300535 200 Reactions
Mir712 Mouse qPCR Template Standard (MI0004696)
Sign In for Pricing
View Details 
LC400434 20 µg
Transketolase (TKT) (NM_001064) Human Over-expression Lysate
Sign In for Pricing
View Details